Snap 8-10mg

Snap-8 10mg

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🔬 SNAP-8 (Acetyl Octapeptide-3) — Overview

SNAP-8, also known as Acetyl Octapeptide-3, is a synthetic cosmetic neuropeptide developed as an extended analog of SNAP-25–derived peptides. It is studied primarily in cosmetic and dermatological research for its ability to influence neuromuscular signaling involved in facial expression, making it relevant to skin appearance and wrinkle-related research models.

📌 Brief Functional Description

• Neuromuscular modulation: Studied for reducing neurotransmitter release at the neuromuscular junction in localized tissue models.
• Expression-line research: Explored for effects on dynamic wrinkles associated with repeated facial muscle contraction.
• Extended activity: Designed to provide greater duration of action compared with shorter SNAP-derived peptides.
• Research relevance: Used in cosmetic science, dermatology, and skin-aging research.

🧪 Chemical & Structural Information

🔢 CAS Number

• 868844-74-0

🧬 Molecular Formula

• C₄₁H₇₀N₁₆O₁₆

⚖️ Molecular Weight

• ≈1,075.2 g/mol (Da)

🧬 Amino Acid Sequence & Structure

• SNAP-8 is an 8-amino-acid linear peptide derived from SNAP-25–related sequences.
• It is N-terminally acetylated, which improves stability and resistance to enzymatic degradation.
• The peptide is designed to interfere with SNARE complex formation, reducing synaptic vesicle fusion in localized research models.

General structural description:

8-amino-acid linear peptide with N-terminal acetylation designed for neuromuscular modulation 

🧠 Mechanism & Biological Context

• SNAP-8 interacts with components of the SNARE protein complex, which mediates neurotransmitter vesicle release.
• By modulating SNARE activity, SNAP-8 reduces acetylcholine release at targeted neuromuscular junctions in experimental systems.
• Unlike botulinum toxin, SNAP-8 does not cause permanent neuromuscular blockade and is studied for reversible, surface-level effects.

⚠️ Safety & Regulatory Notes

• Cosmetic research ingredient: SNAP-8 is not FDA-approved as a drug.
• Commonly used in topical cosmetic formulations and experimental dermatologic research.
• Effects are localized and concentration-dependent in research models.

🧪 Quick Reference