CAS Number
- 42464-96-0 — the widely used registry number for 5-Amino-1MQ.
Chemical Name & Formula
- Name: 5-Amino-1-methylquinolinium (often as iodide salt).
- Molecular Formula (cation): C₁₀H₁₁N₂⁺.
Molecular Weight
- ~159.21 g/mol for the quinolinium cationic compound.
- If formulated as the iodide salt (C₁₀H₁₁N₂·I) (common for research supplies), the overall molecular weight is ~286.11 g/mol.
Chemical Structure
- 5-Amino-1MQ is based on a methylated quinolinium scaffold with an amino substitution at the 5 position and a quaternary ammonium center at the 1 position of the quinoline ring system.
- It is typically supplied as a salt (e.g., iodide) in research settings to improve stability and handling.
Mechanism of Action (Research Context)
- Acts as a NNMT inhibitor, reducing the methylation of nicotinamide and potentially preserving nicotinamide for NAD⁺ salvage pathways, which has implications in metabolic regulation and NAD⁺-dependent processes in cellular studies.